Pro-Enbis Industrial Seminar

Design of clinical trials by MetaGen
5th February, 2004


Tony Greenfield (TG)Greenfield Consultants (GREENF.CC)(CR6)
Ron S. Kenett (RK) KPA Ltd. (KPA)(MB32)
András Zempléni (AZ) Eötvös Loránd University (UEOT.DPTS) (MB15)

Dates of the Seminar:

SessionDateTopic Professor
1 10.00-10.30 Introduction (general, Meta, Gen, Minitab) AZ,TG,RK
2 10.30-11.30 Design of trials by Meta 1 TG
3 11.50-13.00 Completion of Meta models TG
4 14.00-16.40 Protocols, simulation by Gen, data analysis, summary TG,RK, AZ

Non attending partners involved

Basic purpose of the seminar

As in Hungary the applications of state-of-the-art metholodogies are somewhat less widespread than in the western half of the continent, we found it important to disseminate the most up-to-date, computer-assisted applications. The participants have got a tool which they can use during their regular work as well as in teaching, so a multiplying effect is awaited.

Activities conducted

Preparation of the presentations, translations to Hungarian, preparation of statistical summary, functions and exercises to the cost-optimal charts worked out.

Software (MetaGen, Minitab) installed to the computers - all of the students worked on their own computers, so altogether 9 computers were used.

Attendance list

 Name Institute address
1 Biacsi, Rea Semmelweis University, Clinic for Child Therapy 1094 Budapest, Tuzoltó u. 7-9
2 Kemény, Sándor BME Vegyipari Muveletek Tanszék 1111 Budapest, Muegyetem rkp. 3.
3 Kertész, Ákos Planiméter Kft. 1136 Budapest, Hollán E.u. 7/b
4 Matúz, Mária University of Szeged, Inst. For Clinical Pharmacology 6726 Szeged, Szikra u. 8.
5 Bönöczk, Péter 1188 Budapest, Damjanich u. 32.
6 Pazonyi, Ilona Richter Gedeon Rt. Budapest 10, Pf. 27.-1475
7 Ori, László University of Pécs 7623 Pécs, Rét u. 27
8 Elek, Péter ELTE TTK Val.elm. és Stat. Tsz. 1117 Budapest, Pázmány P. sétány 1/C
9 Vasas, Krisztina ELTE TTK Val.elm. és Stat. Tsz. 1117 Budapest, Pázmány P. sétány 1/C

Outcomes from seminar

The experience helps to eliminate the minor errors found in the simulation software. The new exercises about economic control charts may be included into the CD (the English translation will soon be ready).

We hope that the established contacts to the participating companies will lead to a continued cooperation and sustained improvement in the area, thus ensuring the realisations of the aims of the Pro-ENBIS project. This type of cross-fertilisation, where practitioners from different background and experience meet is the most effective for finding the best solutions for real-life problems.